Liverpool have been dealt a huge blow ahead of their clash with Manchester City with the news that Virgil van Dijk will miss the game through injury.

The Liverpool Echo report that the Dutch defender has sustained a hamstring injury and is unlikely to be risked against the league leaders.

It is believed that the injury is not serious, but enough to keep him out of the game against Pep Guardiola’s side.

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Liverpool fans would have been eagerly awaiting the chance to see van Dijk at Anfield in the Premier League after his impressive debut against Everton in the FA Cup.

Croatian defender Dejan Lovren is expected to return to the back four to partner Joel Matip.

Liverpool know that if they could move as high as second in the table if they become the first team to beat Manchester City this season.

The Reds are three points behind Chelsea and Manchester United, with the latter not playing until Monday night.